US Stock Market top gainers and losers on October 29, 2025: Cambium Networks Corporation sees 377% jump, Quhuo Limited plunges; here’s how NASDAQ, Dow Jones, S&P 500 performed

The impact of the Federal Reserve interest rate cut reflected on Wall Street on Wednesday (October 30, 2025) as the Dow ended lower and the S&P 500 finished The Nasdaq registered another record closing high, boosted by Nvidia after the AI chipmaker made history as the first company to reach $5 trillion in market value. In earlier trading, stocks rose and then added to gains after the Fed cut interest rates by a quarter of a percentage point, as expected, and said it will restart limited purchases of Treasury securities.

Fed policymakers also noted the limits in their decision-making process due to the U.S. federal government shutdown. The Fed lowered the overnight benchmark rate to a target range of 3.75% to 4.00%, the second time the U.S. central bank eased this year. After Powell spoke, traders pared bets on a December rate cut, giving it a 71% chance, down from 90%.

Nvidia's stock ended the session up 3% at $207.04, giving it a stock market value of $5.03 trillion. It has risen more than 50% this year, leading the artificial intelligence rally on Wall Street. The Dow Jones Industrial Average fell 74.37 points, or 0.16%, to 47,632.00, the S&P 500 lost 0.30 points to 6,890.59 and the Nasdaq Composite gained 130.98 points, or 0.55%, to 23,958.47.


Among Wednesday's key results, Caterpillar reported a third-quarter profit that beat expectations, and its shares jumped 11.6%. After the closing bell, shares of Meta Platforms, Microsoft and Alphabet were mixed following quarterly reports by the three megacaps.

Shares of Meta Platforms were down more than 8% in extended trading, while Microsoft was down 1% and Alphabet was up about 5%.

Declining issues outnumbered advancers by a 2.16-to-1 ratio on the NYSE. There were 476 new highs and 170 new lows on the NYSE. On the Nasdaq, 1,453 stocks rose and 3,306 fell as declining issues outnumbered advancers by a 2.28-to-1 ratio. Volume on U.S. exchanges was 20.71 billion shares, compared with the 21 billion average for the full session over the last 20 trading days.

Check top gainers and losers on NASDAQ

As of October 29, 2025, at 4:15 PM ET, several stocks showed significant movement, with some advancing sharply and others declining steeply.

Among the most advanced stocks, Cambium Networks Corporation (CMBM) led the list with an impressive gain of +377.3463%. It was followed by Prenetics Global Limited (PRENW), which rose +96%, and VSee Health, Inc. (VSEEW), which advanced +85.0136%. Purple Biotech Ltd. (PPBT) also saw a notable increase of +81.6935%, while Nuveen Global High Income Fund (JGH) gained +79%.

On the other hand, the most declined stocks showed steep losses. Quhuo Limited (QH) dropped by -84.4828%, marking the sharpest decline of the day. Advent Technologies Holdings, Inc. saw significant losses across two listings, with ADNWW down -71% and ADN down -66.107%. Stride, Inc. (LRN) also declined by -54.2109%, while RiverNorth/DoubleLine Strategic Opportunity Fund, Inc. Common Stock fell by -52.381%.