What is 'Ozempic Feet'? The painful side effect of the controversial weight loss drug affecting celebrities

A concerning side effect of Ozempic and similar weight loss medications has come to light—dubbed "Ozempic feet", according to recent findings. While these prescribed drugs are effective in aiding weight loss, they have been linked to various aesthetic complications, including skin laxity that may affect the dorsal region of the feet, as reported by The Daily Mail.

Dr. Barry Weintraub, speaking to The Daily Mail, explained that Ozempic and other semaglutides like Mounjaro significantly reduce fat deposits and water retention. This impact is most noticeable in areas with delicate subcutaneous fat layers, such as the tops of the feet.

According to the report, several celebrities are believed to be experiencing this unusual side effect. One such case involved Sharon Osbourne, who reportedly lost 42 pounds using the medication. In a recent Instagram photo with her grandson, observers noted visible wrinkling on her feet, attributing the changes to the drug rather than natural aging, according to The Daily Mail.


Even Oprah Winfrey, 71, is said to be dealing with similar issues. Winfrey previously disclosed her use of weight-loss medication during a televised appearance last year. Critics have pointed out that she too appears to show foot-related changes possibly linked to Ozempic use, the report claims.

A growing list of public figures have acknowledged using GLP-1 medications, including Pennsylvania Senator Jon Fetterman, comedian Amy Schumer, and X owner Elon Musk. Originally developed to manage type 2 diabetes, these drugs are now widely used for weight loss—but not without cosmetic and physiological trade-offs.