World Alzheimer's Day: Too much stress is toxic, can damage your brain

Along with stress, hypertension also play an important role in Alzheimer’s.

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You may be losing as much as 1% of your brain mass every year.
By Dr Suryanarayana Sharma

Even if you seem perfectly healthy, you may be losing as much as 1% of your brain mass every year. The rate of brain shrinkage increases with age and is a major factor in early cognitive decline and premature death.

Alzheimer’s disease is the most common form of dementia. Common age of onset of the disease is above 65 years. Early-onset Alzheimer's disease occurs between a person's 30s to mid-50s. There are several factors influence when Alzheimer's disease begins and starts to progress.


A host of factors beyond genetics may play a role in the development and course of Alzheimer's disease. There is a great deal of interest, for example, in the relationship between cognitive decline and cardiovascular conditions such as heart disease, stroke, and high blood pressure, as well as metabolic conditions such as diabetes and obesity.

When a person has Alzheimer’s, his brain changes. It has fewer healthy neuron controlling memory, and it gets smaller over time. Plaques damage the healthy brain cells around them. The damaged cells die, and the brain shrinks. These changes cause the symptoms of Alzheimer’s, such as memory loss, speech problems, confusion, and mood swings.

With Alzheimer’s disease there is great individual variability as to the nature of symptoms experienced and the speed at which deterioration occurs. The types of behaviour change and the length of time symptoms are present are different for each person. The symptoms of Alzheimer's disease typically develop quite slowly.
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Stress and hypertension play an important role in Alzheimer’s. Whenever an individual feels stress, the body releases stress hormones like adrenaline and cortisol to cope with the situation causing the discomfort. However, too much stress becomes toxic; elevated cortisol levels may have a negative impact on cognition and lead to higher chances of developing Alzheimer’s disease.

Symptoms commonly experienced during the early stages of Alzheimer's disease include:
- Mild forgetfulness – especially short-term memory loss
- Mood changes, including irritability and anxiety
- Difficulty processing new information and learning new things
- Loss of spontaneity and initiative
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- Confusion about time and place
- Communication difficulties
- Decline in ability to perform routine tasks.

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As Alzheimer’s disease progresses the following symptoms may develop:
- Increasing short-term memory loss and confusion
- Difficulty recognising family and friends
- Shorter attention span and feelings of restlessness
- Difficulty with reading, writing and numbers
- Possibly neglectful of hygiene
- Loss of appetite
- Personality changes (eg: aggression, significant mood swings)
- Requires increasing assistance with daily tasks.
- Change in sleep pattern


Patients with memory loss and presenting like Alzheimer's disease must be carefully evaluated for treatable conditions such as hypothyroidism, Vitamin B12 deficiency, stroke and subdural hematoma as treatment of these conditions greatly improve patients condition.

Although there are no specific dietary specifications for Alzheimer's, a Mediterranean-style diet (i.e: plant foods such as vegetables, fruits, beans, whole grains, nuts, olives and olive oil, along with some cheeses, yoghurt, fish, poultry and eggs) may reduce the risk of Alzheimer's disease. Good control of diabetes, hypertension ,high cholesterol and heart problems may delay the progression of the disease.

Moving more might help to keep people’s brains sharp as one getting 40 and older– even in the face of Alzheimer’s. Mental activities included intellectual activities, such as reading and writing; artistic activities, such as going to a concert or singing in a choir; socialising with like-minded groups, manual activities, such as gardening and indoor games may be tied to a lower risk of developing Alzheimer’s decades later.

(The author is senior consultant neurologist and stroke specialist at Apollo Hospitals Bannerghatta, Bangalore)

World Parkinson's Day: Coffee, Nuts & Fish Can Boost Brain Power
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Parkinson's Disease, a neurodegenerative disorder, is affecting the ageing population's mobility and locomotion.

The disabling disease occurs in elderly (between age 50 and 65) when the brain cells get damaged. The brain's natural chemical 'dopamine' is in charge of the nerve cell communication. The disease develops when the brain is unable to produce dopamine, and starts abnormally storing a protien called 'Lewy bodies' in substantia nigra, a part which controls movement.

The symptoms of the disease - rest tremors, bradykinesia or slow movements, and muscle stiffness or rigidity - develop gradually over the years. In most cases the cause of the condition is not known.

On World Parkinson's Day, here are few food items that can boost your cognitive skill, and keep the disease at bay.
Parkinson's Disease, a neurodegenerative disorder, is affecting the ageing population's mobility and locomotion. The disabling disease occurs in elderly (between age 50 and 65) when the brain cells ..
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According to a study conducted by Sweden's Chalmers University of Technology, a protein called parvalbumin - which is common in many fish species -can improve long-term cognitive health. The fish protein uses the Parkinson's protein for its own use, preventing them from harming the brain cells.
According to a study conducted by Sweden's Chalmers University of Technology, a protein called parvalbumin - which is common in many fish species -can improve long-term cognitive health. The fish pro..
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Two studies published in the Journal of Frontiers in Neuroscience and Proceedings of the National Academy of Sciences emphasise on the importance of coffee in combating against Parkinson's disease.

The Journal stressed the roasting process of coffee beans. When coffee is roasted, it generates Phenylindanes that inhibits two proteins - beta-amyloid and tau - from clumping. Hence, dark roasted coffee beans are better than light roasted as the process leads to higher phenylindanes quantities.

The other study suggested that a new compound found in coffee - EHT (Eicosanoyl-5-hydroxytryptamide - can fight against Parkinson's disease.
Two studies published in the Journal of Frontiers in Neuroscience and Proceedings of the National Academy of Sciences emphasise on the importance of coffee in combating against Parkinson's disease. ..
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A study submitted by the University of Sao Paulo in Brazil says that consuming a low-calorie diet can protect the brain from neuronal cell death that can lead to Parkinson's. It also said that eating more calories directly influences the performance of various cells.
A study submitted by the University of Sao Paulo in Brazil says that consuming a low-calorie diet can protect the brain from neuronal cell death that can lead to Parkinson's. It also said that eating..
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According to a study published in the journal Redox Biology, a native California shrub - Yerba santa (Eriodictyon californicum) - holds the key to reversing neurological disease symptoms.

The plant contains a compound called Sterubin that removes iron, which contributes to nerve cell damage in neurodegenerative diseases.

The shrub is also known for treating respiratory ailments, fever and headaches.
According to a study published in the journal Redox Biology, a native California shrub - Yerba santa (Eriodictyon californicum) - holds the key to reversing neurological disease symptoms. The plant ..
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The study by researchers from the University of South Australia have found out that eating more than 10 grams of nuts every day (preferably peanuts) can keep age-related mental disorders at bay. People who eat 2 teaspoons of nuts daily can improve their cognitive skills by up to 60 per cent, compared to people who don't.

Add these superfoods to your diet, and keep your brain healthy.
The study by researchers from the University of South Australia have found out that eating more than 10 grams of nuts every day (preferably peanuts) can keep age-related mental disorders at bay. Peop..
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(Disclaimer: The opinions expressed in this column are that of the writer. The facts and opinions expressed here do not reflect the views of www.economictimes.com.)
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