'Who are you?' he asked his wife before his daughter's wedding. CT scan, MRI reports normal. Neurologist points out the real culprit
A 60-year-old father's memory loss and behavioral changes during his daughter's wedding were initially blamed on stress. Medical tests were normal, but a seizure led to further investigation. Neurologists diagnosed autoimmune encephalitis. Prom...

Dr Sudhir Kumar, a renowned neurologist, took to X and narrated the case of a 60-year-old father whose life was revolving around one of its most emotional milestones: his daughter’s wedding. According to Dr Kumar, the man was in good spirits initially. The household was filled with the usual excitement that comes with wedding preparations. Conversations about venues, shopping lists, guest arrangements, and celebrations had begun to take over daily life. It was a moment the family had long been waiting for. But gradually, subtle changes began to appear in his behaviour.
One evening, he looked at his wife and asked a question that left her momentarily confused. He asked who she was. At first, it was dismissed as a joke or a harmless slip. The family laughed it off, assuming it was exhaustion or stress from planning the wedding. However, the same question resurfaced the next day. And then again. What seemed like isolated confusion soon became a pattern.
Memory issues
As time passed, his memory issues deepened. He began forgetting not just names, but also the context of ongoing events. He questioned why they were booking a hotel. He asked why shopping was happening. He even asked what all the preparations were for, despite being part of the planning process himself.At this point, his wife and daughter grew increasingly concerned. Yet, like many families in similar situations, they initially attributed the changes to emotional stress. Wedding planning is often intense, and it was easy to assume that the pressure was affecting his mental clarity.
Sudden seizure
Within a week, he experienced a sudden seizure. This marked a turning point for the family. What had seemed like stress now appeared far more serious. He was referred for neurological evaluation. Dr Sudhir Kumar explained that when he first met the family, the pattern of symptoms raised immediate concern. Memory loss, behavioural changes, and now seizures did not align with a simple stress-related diagnosis. These were warning signs suggesting an underlying neurological condition.A detailed medical investigation followed. An MRI of the brain with contrast was conducted, but the results appeared normal. A cerebrospinal fluid test showed only mild abnormalities. An EEG also failed to provide a clear diagnosis. Despite inconclusive results, the clinical pattern remained troubling. Dr Kumar highlighted that medicine often requires attention to symptom patterns even when tests do not immediately reveal answers.
PET Scan report
To investigate further, a PET scan of the brain was performed along with an autoimmune encephalitis panel. This time, the diagnosis became clear. The patient was suffering from autoimmune encephalitis, specifically related to anti-NMDA receptor antibodies. This condition occurs when the body’s immune system mistakenly attacks brain cells, leading to symptoms such as memory loss, behavioural changes, seizures, and in severe cases, coma.Treatment
Over the following days and weeks, gradual improvement was observed. Slowly, recognition returned. He began identifying family members again. Conversations resumed. Emotional connection, which had been disrupted by illness, started to re-emerge.Dr Sudhir Kumar concluded that this case serves as an important reminder that not all memory loss is caused by stress or psychological strain. Sometimes, the brain is affected by underlying medical conditions that require timely recognition and intervention. Early diagnosis, he emphasised, can make the difference between prolonged suffering and meaningful recovery.
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