Scientists are developing an eye drop to treat age-related vision loss
Technology behind the eye drops is a cell-penetrating peptide that can deliver drug to the retina.
By PTI |
LONDON: Scientists are developing an eye drop that could revolutionise the treatment for age-related macular degeneration (AMD), the leading cause of blindness in the developed world.
It is estimated that, by 2020, there will be about 200 million people worldwide with the condition, according to researchers at the University of Birmingham in the UK.
AMD is currently treated by injections of sight-saving drugs into the eye which must be administered by medical professionals.
Now, scientists have invented a method of delivering these otherwise-injected drug as eye drops.
The scientists investigated the effect of the eye drops in the eyes of rabbits and pigs, which are more similar to human eyes.
Their study, published in the journal Investigative Ophthalmology & Visual Science (IOVS), demonstrates that the eye drops can deliver a therapeutically effective amount of the drugs to the retina of the larger mammalian eye.
ADVERTISEMENT
The technology behind the eye drops is a cell-penetrating peptide that can deliver the drug to the retina (the back of the eye).
The scientists' pending patents for the eye drops are now owned by US-based company, Macregen Inc, and a team of Birmingham researchers is working with the company to develop a novel range of therapies for AMD and other eye diseases.
The combined team is now expediting proof of concept studies to confirm the validity of the therapeutic approach, researchers said.
Clinical trials will be imminent once these studies are completed, and could start as early as spring 2019, they said.
ADVERTISEMENT
"For several years, our team has focused on the challenge of delivering drugs to the back of the eye," said Felicity de Cogan, from the University of Birmingham's Institute of Microbiology and Infection.
"From the outset, we realised that delivering drugs through eye drops would mean that patients can administer their treatment themselves, and this would be less costly, save time for patients and healthcare providers, and reduce the potential complications that can arise from injections," de Cogan said.
ADVERTISEMENT
World No Tobacco Day: Smoking Can Hurt Eyes, Bones And Brain
1/10
Most smokers believe smoking is cool. No matter how you indulge in it, tobacco is harmful to your health. Tobacco contains over 7,000 toxins and 70 known carcinogens (chemicals that increase cancer risk) and can damage nearly every organ of the body.
Dr Sachin Kumar, Senior Consultant - Pulmonology at Sakra World Hospital explains how smoking affects every part of your body.
The next time you are tempted to take a drag, just pause for a minute and think of the consequences of your indulgence.
Most smokers believe smoking is cool. No matter how you indulge in it, tobacco is harmful to your health. Tobacco contains over 7,000 toxins and 70 known carcinogens (chemicals that increase cancer r..
Read More
Smoking usually helps smokers relax on a short-term basis. But, it comes at a huge price in the long-term. Smoking results in addiction and anxiety. It alters the brain chemistry and can increase the risk of stroke.
Smoking usually helps smokers relax on a short-term basis. But, it comes at a huge price in the long-term. Smoking results in addiction and anxiety. It alters the brain chemistry and can increase the..
Read More
Cancer of mouth and throat is common among smokers. In addition, smoking can also result in gum disease, premature tooth loss, discolouration of teeth, etc.
Cancer of mouth and throat is common among smokers. In addition, smoking can also result in gum disease, premature tooth loss, discolouration of teeth, etc.
Lung cancer, one of the leading causes of death in the world, develops due to smoking. Chronic Obstructive Pulmonary Disease which causes difficulty in breathing is another common cause of death among smokers. Chronic Bronchitis, the inflammation of the bronchial tubes which also results in difficulty in breathing, is caused primarily due to smoking.
Smoking also increases the risk of other infections like pneumonia, tuberculosis, etc.
Lung cancer, one of the leading causes of death in the world, develops due to smoking. Chronic Obstructive Pulmonary Disease which causes difficulty in breathing is another common cause of death amon..
Read More
Smoking is one of the leading causes for heart diseases. Regular smokers, as well as second-hand/passive smokers, are at high risk of heart disease.
Tobacco also contributes to heart conditions by reducing the good cholesterol (HDL) and increasing the bad cholesterol (LDL and Triglycerides) in the body.
Smoking is one of the leading causes for heart diseases. Regular smokers, as well as second-hand/passive smokers, are at high risk of heart disease.
Tobacco also contributes to heart conditions by r..
Read More
In men, smoking can result in abnormality of sperm, impotence, erectile dysfunction and prostate cancer.
In women, smoking can result in infertility, miscarriage, early menopause, and cervical and ovarian cancer.
Smoking can impact the future generation, and can lead to physical deformities and sudden infant deaths.
In men, smoking can result in abnormality of sperm, impotence, erectile dysfunction and prostate cancer.
In women, smoking can result in infertility, miscarriage, early menopause, and cervical and ..
Read More
Smoking increases the risk of eye-related problems like stinging, excessive tearing, glaucoma and cataract. It can result in partial or total blindness if untreated.
Smoking increases the risk of eye-related problems like stinging, excessive tearing, glaucoma and cataract. It can result in partial or total blindness if untreated.
The kidney's main function is to clear the toxic wastes from our body. But, smoking does exactly the opposite.
It increases the chances of kidney failure, bladder cancer and other urinary tract-related problems.
The kidney's main function is to clear the toxic wastes from our body. But, smoking does exactly the opposite.
It increases the chances of kidney failure, bladder cancer and other urinary tract-rela..
Read More
Bones provide structure to the body. Due to the toxins present in tobacco, smoking can result in osteoporosis (weakening of the bones), increasing the risk of hip fracture, spine-related problems, bone marrow cancer and also rheumatoid arthritis.
In addition to the above-mentioned problems, tobacco can also result in premature ageing, hair loss, weak immunity etc.
Bones provide structure to the body. Due to the toxins present in tobacco, smoking can result in osteoporosis (weakening of the bones), increasing the risk of hip fracture, spine-related problems, bo..
Read More
Smoking reduces appetite. It prevents adequate nutrition to the body which makes the body weak. It can also up the insulin resistance of the body which makes people susceptible to type 2 diabetes. It also has a negative impact on the liver and intestine, and can increase the risk of ulcers in the stomach and intestine.
Smoking reduces appetite. It prevents adequate nutrition to the body which makes the body weak. It can also up the insulin resistance of the body which makes people susceptible to type 2 diabetes. It..
