Global fight against Covid: Here comes a new vaccine pill
ET Online |
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Oral vaccination
An investigational COVID vaccination that can be given orally has been found to protect the host while also reducing the virus's airborne transmission to unprotected people.
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Vaccine test
Dr. Langel and colleagues tested a vaccine candidate that uses an adenovirus as a vector to express the spike protein used by SARS-CoV-2 to gain entrance to cells.
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On hamsters
The scientists tested their vaccine candidate on hamsters and generated intranasal and oral versions.
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Production of immunoglobulin
The experimental vaccination works by increasing the production of immunoglobulin A, the immune system's first line of defence against infections, in the mucosal tissues of the nose and lungs.
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Conclusion
The study concluded that oral immunisation strategies should be investigated for vaccination initiatives that promote global immunity.