Cancer therapy has several side-effects; increases risk of heart disease & diabetes in men

Side-effects of the hormone therapy include loss of muscle mass and fat gain.

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MELBOURNE: A cancer therapy - considered to be gold-standard treatment - is causing men to lose muscle mass and gain fat, putting them at increased risk of other disorders like cardiovascular disease, diabetes and osteoporosis, a study has found.

Researchers from Deakin University in Australia showed men treated with hormone therapy for prostate cancer often had a dangerously high fat to muscle ratio.

The study said while the five-year survival rate for Australian men with prostate cancer was now 95 per cent, side-effects from the intense treatment regimen were becoming an increasing concern.


"Men diagnosed with prostate cancer are now living longer due to medical advancements, but are susceptible to a range of treatment side-effects," said Patrick Owen, lead author of the study published in the Journal of Cachexia, Sarcopenia and Muscle.

"Prostate cancer survivors are now more likely to die from other conditions, such as cardiovascular disease, than prostate cancer, which may in part be due to our inability to detect and subsequently treat side-effects of therapy," Owen said in a statement.

Preventing Cancer: Daily Exercise, Veggies, No-Smoking
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A study by the National Institute of Cancer Prevention and Research on Cancer shows that 11,57,294 lakh new cases are registered in India every year, and 7,84,821 people succumbed to the disease in 2018.



Here are certain lifestyle changes that can keep cancer away.

A study by the National Institute of Cancer Prevention and Research on Cancer shows that 11,57,294 lakh new cases are registered in India every year, and 7,84,821 people succumbed to the disease in 2..
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Being overweight and obese raise risk for breast, colorectal, oesophageal, uterine, pancreatic and kidney cancers.

It is important to manage your weight. Be as lean as possible without becoming underweight.

It is essential to be physically active. Workout for at least 30 minutes every day to stay fit.
Being overweight and obese raise risk for breast, colorectal, oesophageal, uterine, pancreatic and kidney cancers. It is important to manage your weight. Be as lean as possible without becoming unde..
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Avoid sugary drinks as much as possible. Limit consumption of high-calorie and salty foods. Also stay away from food items processed with salt.
Avoid sugary drinks as much as possible. Limit consumption of high-calorie and salty foods. Also stay away from food items processed with salt.
Smoking remains the largest preventable cause of throat and lung cancers in the world. Avoid smoking and second-hand smoking.
Smoking remains the largest preventable cause of throat and lung cancers in the world. Avoid smoking and second-hand smoking.
Alcohol consumption plays an important role in getting various cancer types. Risk of breast cancer is also increased by alcohol — the more you drink, the more likely you get the disease. It is also strongly linked to mouth and upper throat cancers. If you drink alcohol, limit your daily intake.
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Eat a variety of vegetables, fruits, whole grains and legumes.

Don’t use supplements unless prescribed
Eat a variety of vegetables, fruits, whole grains and legumes. Don’t use supplements unless prescribed
Diet high in red and processed meats contribute to bowel cancers. Limit consumption of red meat and avoid processed meats.
Diet high in red and processed meats contribute to bowel cancers. Limit consumption of red meat and avoid processed meats.
It’s necessary for mothers to exclusively breastfeed their babies up to six months.
It’s necessary for mothers to exclusively breastfeed their babies up to six months.
After treatment, cancer survivors should follow professional recommendation to prevent secondary cancer.
After treatment, cancer survivors should follow professional recommendation to prevent secondary cancer.

"It's critical we are able to quickly and easily identify modifiable risk factors for these other conditions," he said.

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"The amount of muscle we have relative to fat is one of the biggest indicators for diabetes risk, decreased physical function needed to complete daily tasks, and lots of other adverse health conditions," he added.

The research examined the muscle and fat in 70 men treated with hormone therapy for prostate cancer compared to 52 men with prostate cancer not treated with hormone therapy and 70 healthy men of a similar age.

It found men treated with hormone therapy for prostate cancer had the same amount of total muscle mass compared to other men in the study, but four to six kilograms more fat mass.

"When muscle was considered in relation to this fat mass, men treated with hormone therapy for prostate cancer had lower fat-adjusted muscle mass, which may predispose them to further health issues," Owen said.

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Metastatic cancer, also known as advanced-stage cancer, starts in one organ and then spread to other organs of the body.

Dr Rucha Kaushik, Consultant, Breast Cancer Surgeon, P D Hinduja Hospital & MRC busts some myths associated with high-grade cancer.

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Also read: 4 treatment options for metastatic cancer that patients can consider

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Fact: The treatment depends on the stage of cancer at the time of diagnosis and the organ(s) involved. The combination of chemotherapy, surgery and radiotherapy form the treatment protocol. Nothing about the treatment is aggressive or non-aggressive. All cancers to be treated with utmost care.

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Fact: Cancer isn't a death sentence. Early detection saves life. Diagnosis at early stage gives better chances of complete cure.

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"When men are diagnosed with advanced prostate cancer they are often treated with hormone therapy to reduce their testosterone levels, which discourages cancer growth. This is considered the gold-standard of treatment," he said.
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"It puts men through the equivalent of menopause. There's a loss of muscle and bone, they gain fat, and even start to have hot flushes," he said.

While men with prostate cancer treated with hormone therapy may have the same or greater absolute muscle mass than non-treated and healthy men, it's not as functional as the same amount of muscle in otherwise healthy weight men.

Owen said he hoped his research would encourage more clinicians to test their patients for muscle mass relative to body fat.

Lifestyle interventions that could be used to help men with prostate cancer reduce body fat and increase muscle.

"Given the current treatment and medical landscape, people are living longer with cancer, so there needs to be a shift in focus towards improving the quality of these additional years of living," Owen said.

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Bollywood actress Sonali Bendre has been undergoing treatment in New York after being diagnosed with metastatic cancer.

While one can never be sure what can trigger the onset of this deadly disease, it is important to take necessary precautions to stay safe. There are certain food items that have anti-carcinogenic properties, and can help in keeping cancer at bay.

These herbs and spices from your kitchen cabinet can boost your immune system to keep the deadly disease at bay. Dr Manoj Kutteri, Director of Atmantan Wellness Centre, shares a list of ingredients that can help your fight the illness.

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Ginger has been considered ten thousand times more powerful than chemotherapy for the treatment of cancer. It is an anti-oxidant and a natural cancer fighter. The active compounds 6-gingerol and 6-shogaol exhibit anti-cancer properties against the gastrointestinal tract and helps in cancer cell death.
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Garlic is another most important spice that is used in treating cancer. It has the ability to inhibit the production of cancer-causing properties, speed up the repairing process of DNA and to decelerate the proliferation of cancer cells.
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This aromatic herb used inn pizzas contain an active ingredient known as carvacrol, which is proven to be beneficial in treating prostate cancers. The oregano oil has the ability to selectively kill the cancer cells while leaving the healthy cells intact.
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